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Mastiff puppies and dogs in El Cajon, California

Looking for a Mastiff puppy or dog in El Cajon, California? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near El Cajon, California Other pups in El Cajon, California Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in El Cajon, California Mastiff shelters and rescues in El Cajon, California Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in El Cajon, California

These Mastiffs are available in El Cajon, California.
Photo of Sakura

Sakura

Mastiff

Female, Young
El Cajon, CA
Size
(when grown) -
Details
Spayed or Neutered,
Story
How this pet arrived: This pet was brought in by a community member on 3/7/25. Why this pet is the one for you:Sakura is an 8-month-old Cane Corso puppy who is still learning to be brave in new situations. She will need a patient family to help her build confidence at her own pace. In addition to her shy nature, she has some medical needs that will require follow-up care. With time, love, and the right support, Sakura has the potential to blossom into a wonderful companion. At SDHS:This pet has been vaccinated, microchipped and spayed/neutered. This pet is now ready for their new home! Primary Color: Black Brindle Weight: 57.6 Age: 0yrs 8mths 1wks

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Photo of Scarlett

Scarlett

Mastiff

Female, Adult
El Cajon, CA
Size
(when grown) -
Details
Spayed or Neutered,
Story
How this pet arrived: This pet was brought in by a community member. Why this pet is the one for you:Scarlett is a sweet, gentle giant with a heart as big as her paws. She loves affection and will happily lean in for pets and cuddles. If you're looking for a loving, loyal companion, Scarlett is ready to fill your home with warmth and joy! At SDHS:This pet has been vaccinated, microchipped and spayed/neutered. This pet is now ready for their new home! Primary Color: Brown Secondary Color: Blue Weight: 101.4 Age: 5yrs 0mths 1wks

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Or, how about these Mastiffs in cities near El Cajon, California

These Mastiffs are available for adoption close to El Cajon, California.
Photo of Jacques-Merced, CA

Jacques-Merced, CA

Mastiff

Male, 1 yr 4 mos
Southern CA, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Location: Merced, CA Handsome hunky boy Jacques is around 11 months old. He was rescued off the streets by a kind elderly lady. No microchip or owner has been found. He is a big boy at 100 lbs and just a bit too much puppy for her to keep him. Jacques is sweet, friendly, a big lump of affection, super loving and great with the 4 yr. old child in the home. He loves car rides and playing in the yard chasing tennis balls. Chew bones are the bestest! He is partially blind in one eye but that doesn't stop him. He has been wonderful with the other dog & puppies that were also rescued off the streets, that are also with the elderly finder. Kitties are unknown. Jacques would make a wonderful addition to any family with his loving disposition. If you think he is the right one for you, reach out to the rescue: Copy & Paste the link below into your browser for our online application: https://www.jotform.com/form/243374218477059 Email us for any further questions: info@savethedals.org

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Photo of Cuddles

Cuddles

Mastiff

Male, Adult
San Diego, CA
Size
(when grown) -
Details
Spayed or Neutered,
Story
How this pet arrived:This pet was brought in by a community member on December 24, 2024. Why this pet is the one for you:Meet Cuddles, a handsome, bashful guy looking for a calm and loving home! Cuddles can be a bit shy with new faces, and appreciates some patience while he builds trust. Once he feels comfortable, he blossoms into a relaxed, easygoing pup! Cuddles has been working with our trainers and has been an excellent student using positive reinforcement techniques. He's a smart boy who enjoys learning, and we'll give you lots of tips to continue his training and help him build confidence. Cuddles will thrive in low-traffic household with a family who can understand his needs and respect his space. If you're ready to offer this sweet guy the gentleness he needs, there will be no limit to the love Cuddles will share with you! Come speak to an adoption counselor to learn more about him today. At SDHS:This pet has been vaccinated, microchipped and spayed/neutered. This pet is now ready for adoption! Primary Color: Grey Secondary Color: Brindle Weight: 87.5 Age: 2yrs 2mths 3wks

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Jughead

Mastiff American Staffordshire Terrier

Male, 2 yrs
San Diego, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Meet Linden! DOB: March 2023Weight: 70lbsDisposition: Friendly, Engaged, HappyHistory: Rescued from a shelter in LA County by TBL in March 2025Best Home: Amazing Qualities: If you're interested in meeting this dog, please visit our website to fill out an adoption application: www.thebarkinglot.net/adoptOur dogs are located in San Diego County, CA. We will happily consider out of town applications and can conduct virtual play dates with interested adopters. We have monthly transport to various locations in the Pacific Northwest, individual arrangements would need to be made for other locations across the US and Canada.To initiate the adoption process for this dog, please complete our online application by clicking below. Your adoption coordinator will respod to you via email once they receive your application: www.thebarkinglot.net/adopt

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Photo of Nala

Nala

Mastiff

Female, Young
San Diego, CA
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with dogs, Good with cats, Spayed or Neutered,
Story
Nala and Mia are 8 months old, we got them from a friend when they were only 3 months old. I’m looking for a new home for Talbots on them either separate or together.

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Photo of Kali

Kali

Mastiff

Female, 5 yrs 10 mos
Ramona, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Meet Kali! 5-year-old Kali and her sister Kara (also available for adoption) were entrusted to our care through the Final Wish Program after their mom passed away. Kali was very loving and devoted to her mom, and with time, she will share her big heart with a new family. She enjoys playing fetch and is good with the 2-year-old granddaughter of her late owner. For the past 5 years, Kali lived with Kara, and they get along very well. They eat alongside each other without issue and share space and attention nicely. Both dogs earned high marks from the care staff where they boarded. Only a few days after becoming a Frosted Face, Kali was chosen for a two-week Frosted Fling. This will help us learn more about her in a home environment while allowing us to see how she and Kara do without the other. Happily, Kara is on a Fling getting lots of love in a home, too! Kali's fling mom shared this great first update: "Kali girl is loving her time at the Ranch! She met her pig and cow friends. We’re still not sure how we feel about cats, if they’re our friends or a toy, so for now we visit the kitties from a distance. Kali loves laying her head on your lap, that’s where she feels the safest. More updates to come when this rain stops, and we can go for walks and hikes!" Check back soon for the next update!

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Photo of Indiana

Indiana

Mastiff

Female, Young
Escondido, CA
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Indiana, a gentle one-year-old Mastiff mix from San Diego, CA, with the soul of a cuddler and a heart full of love. Weighing in at a "petite" 67 pounds, this tan beauty with striking dark facial features is a calm and loyal companion who loves to be the center of attention! Indy, as her friends call her, is the perfect blend of low energy and sweetness. She’s spayed, vaccinated, microchipped, house-trained, crate-trained, leash-savvy, and knows all her basic commands. Plus, she comes with a fantastic bonus: unlimited training sessions through Bark Busters (easily transferred to her new family). She’s already an obedient girl, but with this resource, she can continue to shine! Indiana is friendly with dogs of all sizes and absolutely adores children but would do best in a single dog environment with older children. Her easygoing nature makes her a great fit for playdates at the park or lounging at home with her favorite people.

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in El Cajon, California.

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Mastiff puppies and dogs in nearby cities

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Related breeds in El Cajon, California

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Mastiff shelters & rescues in El Cajon, California

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in El Cajon, California. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

5.4 miles

San Diego Humane Society - El Cajon Campus

1373 N. Marshall Ave., El Cajon, CA 92020

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

12.7 miles

Save the Dalmatians and Others Canine Rescue, Inc

San Diego, Orange County, Los Angeles, California, dogs are fostered in So California, Southern CA, CA 92104

Pet Types: dogs

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Shelter

17 miles

San Diego Humane Society - San Diego Campus

5500 Gaines Street, San Diego, CA 92110

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

18.1 miles

The Barking Lot

San Diego, CA 92117

Pet Types: dogs

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Rescue

20.6 miles

Frosted Faces Foundation

1448 Pine St, Ramona, CA 92065

Pet Types: cats, dogs

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Rescue

38.7 miles

Underdog Heroes

Riverside, CA 92058

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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