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Mastiff puppies and dogs in Des Moines, Iowa

Looking for a Mastiff puppy or dog in Des Moines, Iowa? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Des Moines, Iowa

These Mastiffs are available in Des Moines, Iowa.
We'll also keep you updated on He-Man's adoption status with email updates.
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He-Man

Mastiff

Male, Puppy
Urbandale, IA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained, Shots are up-to-date,
Story
Born March 2019 and was not neutered. He is a great guard dog and has been great with my 2yo and 3yo children their whole lives. He eats Purina One large breed dog food. He is hesitant and will bark at new people until you let him know they are ok. Tall men make him skittish until they sit and he can sniff them. He has never bitten anyone or anything but will bark if strangers make fast movements towards him. Basically a big lovable lap dog that is just 150 lbs. He is very protective of you and your property. Looking for a home that he will be loved and played with since he is active.
We'll also keep you updated on Daisy's adoption status with email updates.
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Daisy

Mastiff Terrier (Unknown Type, Medium)

Female, Young
Des Moines, IA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Daisy!Daisy is a 1-year-old, 65-pound Mastiff mix with a heart as big as her paws! Rescued as a stray in poor condition, Daisy has been thriving in her foster home and steadily gaining weight. She’s blossomed into a sweet, loving girl who adores bedtime cuddles and following her humans everywhere—they’ll never be alone with her around!Still a playful pup, Daisy has plenty of energy and is house trained and still learning the ropes of training like not jumping on you in excitement. She’s a smart cookie and eager to please, so with patience and consistency, she’ll become an amazing companion. Daisy loves playing with bigger, higher-energy dogs, like her foster family’s huskies, and has shown promise around cats. While she’s still learning to respect feline boundaries, she’s making great progress.Watching Daisy discover toys and grow into her happy, playful self is nothing short of heartwarming. She’s ready to bring her big heart and loyal spirit into a forever home that will love her unconditionally. Could Daisy be your perfect match?IMPORTANT: Please read all below, especially if you live outside of Texas, which is where our rescue is located.Apply to adopt on our website: https://www.charmingpetrescue.org/adoptAll of our animals are spayed/neutered, microchipped, and up to date on shots.ALL of our animals are located in Boerne, TX, but transport after adoption is available to other states for a $300 fee for dogs or an additional fee varying by location for cats. If you are seeing our pets posted in your state, that's because you live near a transport stop, they are not currently at that location. Petfinder lists our pets as 'Out of Town' pets at other locations, and Adopt-a-Pet lists our location as a Transport stop. Those are currently the only options they offer to make this clear, so we put this description we've put at the bottom to explain it. You can read more about transport here: www.charmingpetrescue.org/transportWe understand transport is not an option for everyone, but we offer it at the cost we pay the transport company for those who wish to adopt from us.February 6, 2025, 10:16 pm
We'll also keep you updated on Daya's adoption status with email updates.
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Daya

English Mastiff Terrier (Unknown Type, Medium)

Female, Young
Des Moines, IA
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Spayed or Neutered,
Story
- Total goofball who loves toys and being silly - Prefers to explore and do their own thing here in the shelter, but will likely open up more once they're in a home environment and have had time to decompress - Enjoys spending time with dogs who have a similar play style - Young, noisy or busy children can be too much for them (mature home recommended) All adoptable dogs and puppies are spayed/neutered, microchipped and up to date on vaccinations (rabies and DA2PPV as appropriate for their age)The ARL's shelter software requires that we choose a primary breed for our dogs. Visual breed identification in dogs is unreliable, so for most dogs we are only guessing at primary breed. We get to know each dog as an individual and do our best to describe each of our dogs based on personality, not breed label. Primary Color: Brindle Weight: 54 Age: 1yrs 1mths 1wks

Or, how about these Mastiffs in cities near Des Moines, Iowa

These Mastiffs are available for adoption close to Des Moines, Iowa.
We'll also keep you updated on CHAP's adoption status with email updates.
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CHAP

Mastiff

Male, 8 yrs
Ames, IA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
-

These pups are in Des Moines, Iowa too!

Below are our newest added Mastiffs available for adoption in Des Moines, Iowa. To see more adoptable Mastiffs in Des Moines, Iowa, use the search tool below to enter specific criteria!
We'll also keep you updated on Hagrid's adoption status with email updates.
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Hagrid

St. Bernard Great Pyrenees

Male, Adult
Des Moines, IA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
Meet Hagrid! Hagrid is a big ol’ sweetheart and a true gentle giant at 100 pounds of love and sloppy kisses. With his mild and laid-back nature, he’s the perfect companion for someone who appreciates a calm and loving dog. He’s about 5 years old and a Great Pyrenees/lab mix. His foster got his dna test done!This big boy enjoys following his favorite person around and being part of your day-to-day life. Hagrid seems to get along well with other dogs, but may be better suited as a loyal solo companion. Hagrid needs a loving family that is willing to provide additional care for him in the future if need be. He has been diagnosed with a MRSP skin infection that may require ongoing care and medication throughout his life to keep him itch free and comfortable. Although MRSP can be treated and cured, there is also a possibility that ongoing treatment may be required. Hagrid is currently responding to his treatment and is a happy, go lucky boy! Are you ready to welcome this big bundle of love into your family and give him the extra care down the road if he needs it?IMPORTANT: Please read all below, especially if you live outside of Texas, which is where our rescue is located.Apply to adopt on our website: https://www.charmingpetrescue.org/adoptAll of our animals are spayed/neutered, microchipped, and up to date on shots.ALL of our animals are located in Boerne, TX, but transport after adoption is available to other states for a $300 fee for dogs or an additional fee varying by location for cats. If you are seeing our pets posted in your state, that's because you live near a transport stop, they are not currently at that location. Petfinder lists our pets as 'Out of Town' pets at other locations, and Adopt-a-Pet lists our location as a Transport stop. Those are currently the only options they offer to make this clear, so we put this description we've put at the bottom to explain it. You can read more about transport here: www.charmingpetrescue.org/transportWe understand transport is not an option for everyone, but we offer it at the cost we pay the transport company for those who wish to adopt from us.March 3, 2025, 11:06 am
We'll also keep you updated on Thane's adoption status with email updates.
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Photo of Thane

Thane

St. Bernard

Male, 3 mos
Clive, IA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, Spayed or Neutered, Shots are up-to-date,
Story
Hi, I'm Thane! I'm still a pup, but I've got a big heart full of love. I'm sweet as can be and I love making friends. I'm playful, and I love toys, especially the squeaky ones. I'm not just about fun and games though, I also enjoy quiet times for cuddles. Life in a shelter is okay, but I dream of a home where I can share my love and joy. If you're looking for a loyal friend who'll bring happiness into your life, then I'm your pup! If you're interested in adopting me, fill out an adoption application online at www.polkcountyhumanesociety.org/adopt where you will also find a link to reserve me for an appointment. Some pets are in foster homes or may already have an appointment scheduled, so the appointment is important to make sure I will be available to meet you when you come. Polk County Humane Society is located in Bolivar, Missouri, but also makes transports to the Denver, CO, Des Moines, IA and St. Louis areas twice monthly. For potential adopters in those areas, we can do a virtual visit using FaceTime or another app. Just request an appointment using the same link, but note that you want the visit to be virtual. We will call you at the time of the visit once it is confirmed. For long distance transports to Colorado and Iowa, there is an additional $100 fee to cover the cost of the transport ($65) and a health certificate from a veterinarian ($35). For transports to St. Louis, the additional fee is $50 to help cover gas. Going that last mile home for our sweet pets! All of our pets are neutered or spayed, have vaccinations appropriate for their age, treated with flea/tick/heartworm prevention, dewormed and dogs are also microchipped. #adoptdontshop ##2335846##

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Mastiff puppies and dogs in nearby cities

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Mastiff shelters & rescues in Des Moines, Iowa

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Des Moines, Iowa. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

1.2 miles

Charming Pet Rescue - IA Transport Stop

Des Moines, IA 50309

Pet Types: dogs

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Shelter

2.7 miles

Animal Rescue League of Iowa Inc.

5452 NE 22nd St, Des Moines, IA 50313

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Shelter

29.4 miles

Ames Animal Shelter

325 Billy Sunday Road, Ames, IA 50010

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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