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Mastiff puppies and dogs in Saint Louis, Missouri

Looking for a Mastiff puppy or dog in Saint Louis, Missouri? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Saint Louis, Missouri

These Mastiffs are available in Saint Louis, Missouri.
We'll also keep you updated on ROOFUS's adoption status with email updates.
Photo of ROOFUS

ROOFUS

Mastiff

Male, 2 yrs 1 mo
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Roofus is a very affectionate and playful dog who loves being around people. He is social and enjoys making new friends, always ready to greet everyone with a wagging tail. Come meet him today!
We'll also keep you updated on BRYNN's adoption status with email updates.
Photo of BRYNN

BRYNN

Mastiff

Female, 4 mos
St. Louis, MO
Size
(when grown) Small 25 lbs (11 kg) or less
Details
Spayed or Neutered,
Story
Brynn is a fun-loving and active dog who’s always up for an adventure! Social and friendly, he loves being around people and exploring new places. His energetic personality makes him the perfect companion for an active home. Come meer her today!
We'll also keep you updated on Bellatrix aka "Willow Eliza"'s adoption status with email updates.
Photo of Bellatrix aka "Willow Eliza"

Bellatrix aka "Willow Eliza"

Mastiff

Female, 7 yrs 4 mos
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Bella is big and beautiful with a personality to match. This six-year-old mastiff mix girl adores people, snuggles, pets, and attention. She is spayed and up-to-date on all her medical care and is heartworm-negative. Bella is a big girl, approximately 65 pounds, so while she is very good with people, she would be best with older kids who can keep up with her size. She is house-trained, and a fenced yard would be best since Bella is a large dog and likes to play. Bella likes her people so much she doesn't want to share and would do best as the only dog in her home. To meet Bella, visit istodaymydayrescue.org to fill out an application. Her adoption fee is $100.
We'll also keep you updated on Finrir's adoption status with email updates.
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Photo of Finrir

Finrir

Mastiff Mixed Breed (Medium)

Male, 4 yrs 9 mos
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Meet Finrir (Finn)! Finrir, affectionately known as Finn, is ready to charm his way into your heart and home! About Finn: Finn is an 85 lb Mastiff mix with a heart as big as his size. He's a gentle giant who thrives on one-on-one attention and would love to be the center of your universe! Despite his size, Finn is a total softie. He's non-destructive and a pro at taking his medicine with ease. While Finn prefers to be the only fur baby in the house due to some dog reactivity, he'll fill your home with enough love to make up for it! What Finn Needs: A loving family who understands his need to be the only pet. Plenty of space for him to stretch out and relax. Someone who enjoys leisurely strolls because Finn walks like a true gentleman on the leash! Interested in Adopting? If you're ready to give Finn the forever home he deserves, reach out to Center for Animal Rescue and Enrichment of St. Louis - CARE STL Let's find this big guy his perfect match! Help spread the word by sharing this post with friends and family. Together, we can help Finn find his happily ever after! #AdoptDontShop #FosterDog
We'll also keep you updated on Rutt's adoption status with email updates.
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Photo of Rutt

Rutt

Mastiff

Male, 4 yrs 8 mos
St. Louis, MO
Size
(when grown) -
Details
Spayed or Neutered,
Story
Hello, My name is Rutt but I will respond to almost anything if you say it nicely. I'm a 4 year old Mastiff mix that enjoys watching TV on the couch and mouthing material. I'm gentle when playing with humans, but have had a bad experience with a small dog and may not do well in homes with small animals. I am a stubborn speedbump that will follow you around to ensure you are not lonely. I am crate and potty trained. I do not like to get in the car, go on long walks, or get into high beds but that just means more times for cuddles on the couch. I may look intimidating but don't let looks fool you, I run from ballons and empty cups. I got my nails done today and the groomer raved about my good behavior. If you want to see if I'm a good fit, please reach out to Care. Love Rutt
We'll also keep you updated on Mikey Boy's adoption status with email updates.
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Mikey Boy

Mastiff American Staffordshire Terrier

Male, 2 yrs 2 mos
St. Louis, MO
Size
(when grown) -
Details
Spayed or Neutered,
Story
-

Or, how about these Mastiffs in cities near Saint Louis, Missouri

These Mastiffs are available for adoption close to Saint Louis, Missouri.
We'll also keep you updated on Beluga's adoption status with email updates.
Photo of Beluga

Beluga

Mastiff American Pit Bull Terrier

Male, 2 yrs 6 mos
East ST Louis, IL
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
Meet Beluga, a stunning brindle boy with a heart as big as his beauty! He wandered right up to one of our animal care workers in the parking lot, looking for a spot to provide him with some warmth and food—and now he’s ready to find a family to call his own. Sweet, loving, and full of charm, Beluga is the total package. Come meet this handsome guy today—he’s ready to be your new best friend! If you are interested in a meet and greet for adoption for Beluga, please fill out an application on our website at www.gatewaypets.org/adopt. If you are interested in learning more about Beluga or the adoption process at GPG, please email placement@gatewaypets.org All of our dogs and cats will be microchipped, spayed or neutered, and up-to-date on vaccinations at the time of adoption. For more photos of Beluga, follow us on Facebook Gateway Pet Guardians and Instagram @gatewaypets ... #gpgBeluga. To view other adoptable pets from our shelter, please visit, www.gatewaypets.org/adopt. Gateway Pet Guardians is proud to offer a variety of mixed breed dogs available for adoption. However, please keep in mind that we rarely know the genetic background of the animals we rescue and, as such, we cannot guarantee the exact breed combinations found within this dog. However, we do not know his/her actual genetic makeup. Just know that this dog is probably a variety of several different breeds that have combined to create one very amazing and unique animal.
We'll also keep you updated on Daisy's adoption status with email updates.
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Daisy

Mastiff Terrier (Unknown Type, Medium)

Female, Young
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Daisy!Daisy is a 1-year-old, 65-pound Mastiff mix with a heart as big as her paws! Rescued as a stray in poor condition, Daisy has been thriving in her foster home and steadily gaining weight. She’s blossomed into a sweet, loving girl who adores bedtime cuddles and following her humans everywhere—they’ll never be alone with her around!Still a playful pup, Daisy has plenty of energy and is house trained and still learning the ropes of training like not jumping on you in excitement. She’s a smart cookie and eager to please, so with patience and consistency, she’ll become an amazing companion. Daisy loves playing with bigger, higher-energy dogs, like her foster family’s huskies, and has shown promise around cats. While she’s still learning to respect feline boundaries, she’s making great progress.Watching Daisy discover toys and grow into her happy, playful self is nothing short of heartwarming. She’s ready to bring her big heart and loyal spirit into a forever home that will love her unconditionally. Could Daisy be your perfect match?IMPORTANT: Please read all below, especially if you live outside of Texas, which is where our rescue is located.Apply to adopt on our website: https://www.charmingpetrescue.org/adoptAll of our animals are spayed/neutered, microchipped, and up to date on shots.ALL of our animals are located in Boerne, TX, but transport after adoption is available to other states for a $300 fee for dogs or an additional fee varying by location for cats. If you are seeing our pets posted in your state, that's because you live near a transport stop, they are not currently at that location. Petfinder lists our pets as 'Out of Town' pets at other locations, and Adopt-a-Pet lists our location as a Transport stop. Those are currently the only options they offer to make this clear, so we put this description we've put at the bottom to explain it. You can read more about transport here: www.charmingpetrescue.org/transportWe understand transport is not an option for everyone, but we offer it at the cost we pay the transport company for those who wish to adopt from us.February 6, 2025, 10:16 pm
We'll also keep you updated on Millie's adoption status with email updates.
Photo of Millie

Millie

Mastiff Labrador Retriever

Female, Adult
Wentzville, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, Needs experienced adopter, House-trained, Spayed or Neutered,
Story
Millie is a 4 year old mastiff/lab mix dog, she is very sweet knows basic commands of sit, lay down, and is kennel trained. We are rehoming due to my children's medical complexities that has made it impossible to care for her like she deserves. She is good around dogs, cats and children. She will come with her kennel, beds, her harnesses, collars, etc.

These pups are in Saint Louis, Missouri too!

Below are our newest added Mastiffs available for adoption in Saint Louis, Missouri. To see more adoptable Mastiffs in Saint Louis, Missouri, use the search tool below to enter specific criteria!
We'll also keep you updated on Thane's adoption status with email updates.
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Photo of Thane

Thane

St. Bernard

Male, 3 mos
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, Spayed or Neutered, Shots are up-to-date,
Story
Hi, I'm Thane! I'm still a pup, but I've got a big heart full of love. I'm sweet as can be and I love making friends. I'm playful, and I love toys, especially the squeaky ones. I'm not just about fun and games though, I also enjoy quiet times for cuddles. Life in a shelter is okay, but I dream of a home where I can share my love and joy. If you're looking for a loyal friend who'll bring happiness into your life, then I'm your pup! If you're interested in adopting me, fill out an adoption application online at www.polkcountyhumanesociety.org/adopt where you will also find a link to reserve me for an appointment. Some pets are in foster homes or may already have an appointment scheduled, so the appointment is important to make sure I will be available to meet you when you come. Polk County Humane Society is located in Bolivar, Missouri, but also makes transports to the Denver, CO, Des Moines, IA and St. Louis areas twice monthly. For potential adopters in those areas, we can do a virtual visit using FaceTime or another app. Just request an appointment using the same link, but note that you want the visit to be virtual. We will call you at the time of the visit once it is confirmed. For long distance transports to Colorado and Iowa, there is an additional $100 fee to cover the cost of the transport ($65) and a health certificate from a veterinarian ($35). For transports to St. Louis, the additional fee is $50 to help cover gas. Going that last mile home for our sweet pets! All of our pets are neutered or spayed, have vaccinations appropriate for their age, treated with flea/tick/heartworm prevention, dewormed and dogs are also microchipped. #adoptdontshop ##2335846##
We'll also keep you updated on CHAMP's adoption status with email updates.
Photo of CHAMP

CHAMP

Bullmastiff

Male, 2 yrs
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Champ is a very good boy who is already housetrained, crate trained, and knows a few commands. He has been around children, cats and other dogs.
We'll also keep you updated on Mae's adoption status with email updates.
Photo of Mae

Mae

Bullmastiff

Female, Adult
St Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
BASICS: Bullmastiff / female / 4 years old CHILDREN: Yes, older than 5 due to size CATS: Unknown DOGS: Male dogs over 30lbs, with slow introduction and supervision PERSONALITY: Medium energy level; Very sweet and affectionate; Enjoys taking naps in the sun or on the couch, exploring outdoors in the yard, walking the neighborhood and LOVES hanging out with people. Loves men! TRAINING: Housebroken, leash trained, knows basic obedience and how to use a dog door SPECIAL NEEDS: None VETTING: Fully vaccinated, spayed, microchipped Ready to give Mae the forever home of her dreams? Fill out our Adoption Application, located The Bullpen Way Station & Sanctuary under the 'work with us' tab. We highly recommend that our potential adopters fill out an online application as soon as possible, as it greatly expedites the process of finding the right dog for your situation. Our dogs are available for adoption nationwide but preference is given to adopters willing to do an in-person meeting. Please understand that our dogs are not adopted on a first-come, first-served basis, but rather we strive for a "perfect placement" so we know that they will not be failed again.

Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Saint Louis, Missouri.

Mastiff puppies and dogs in nearby cities

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Related breeds in Saint Louis, Missouri

Mastiff shelters & rescues in Saint Louis, Missouri

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Saint Louis, Missouri. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

4.8 miles

Animal Protective Association of Missouri

1705 South Hanley Road, St. Louis, MO 63144

Pet Types: cats, dogs, rabbits, small animals

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Rescue

6.4 miles

Is Today My Day Rescue

St. Louis, MO 63139

Pet Types: dogs

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Shelter

10.6 miles

CARE STL

2700 Walnut Place, St. Louis, MO 63103

Pet Types: cats, birds, dogs, farm animals, rabbits, small animals

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Rescue

14.2 miles

Gateway Pet Guardians

725 N 15th St, East ST Louis, IL 62205

Pet Types: cats, dogs

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Rescue

16.4 miles

Charming Pet Rescue - MO Transport Stop

St. Louis, MO 63303

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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