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Great Dane puppies and dogs in Saint Louis, Missouri

Looking for a Great Dane puppy or dog in Saint Louis, Missouri? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane near you in Saint Louis, Missouri

These Great Danes are available in Saint Louis, Missouri.
We'll also keep you updated on Franklin's adoption status with email updates.
Photo of Franklin

Franklin

Great Dane German Shepherd Dog

Male, 1 yr 10 mos
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Hello there, I'm Franklin! I'm as sweet as a sugar cookie and friendly as your best pal. My heart is full of gentle kindness and cuddly warmth. I'm always ready for a belly rub or a good old game of fetch. I'm loyal too, like a true companion. I promise to be there for you, through thick and thin, always wagging my tail in joy. I may be living in a shelter now, but what I really want is a forever home. Why should you adopt me? Well, imagine having a friend who loves you unconditionally, who's always excited to see you, and who can turn even a regular walk into an adventure. That's me, Franklin! ##2231302##
We'll also keep you updated on Harley's adoption status with email updates.
Photo of Harley

Harley

Great Dane

Female, 2 yrs 2 mos
St. Louis, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
WE ARE A TX BASED RESCUE. THIS DOG IS CURRENTLY LOCATED IN TX AND WILL BE TRANSPORTED UPON ADOPTION. Please fill out an adoption application found at haydudeequine.org Harley - You are the bridge between what was and what will be, my pathway to a new life! Hello all you fantastic people out there, let me introduce myself. My name is Harley and I'm here hoping to adopt me a family...one that I can say will be all mine! And I'm really hoping since you're reading this, you are considering adding ME to be part of your family!! I am about 2 years old and come in at around 104lbs. Yes, that's a big gal but I'm sweet and loving and well...that's just a little bit more of me to love you!! I have a very sweet loving temperament that does well with people both tall and small and the other foster pups here. Although I haven't had the pleasure yet of meeting any of those strange creatures y'all call a cat I'm not to fond of barnyard critters. I am housetrained already, making it easy for us to get right to the fun stuff...right away. I'd love to share all your adventures from the mundane daily to the weekend exciting. I love getting pets, going for strolls, hiking nature trails, and love anything soft like my big squishy bed or the couch!! If you're ready for lots of love and affection, I is that big gal for you! All you need to do is fill out my adoption application and I will do the rest!! You can find it at haydudeequine.org
We'll also keep you updated on Stormy's adoption status with email updates.
Photo of Stormy

Stormy

Great Dane

Female, 2 yrs 8 mos
St. Louis, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
WE ARE A TX BASED RESCUE. THIS DOG IS CURRENTLY LOCATED IN TX AND WILL BE TRANSPORTED UPON ADOPTION. Please fill out an adoption application found at haydudeequine.org Stormy - You are the bridge between what was and what will be, my pathway to a new life! Hello all you fantastic people out there, let me introduce myself. My name is Stormy and I'm here hoping to adopt me a family...one that I can say will be all mine! And I'm really hoping since you're reading this, you are considering adding ME to be part of your family!! I am about 2.5 years old and come in at around 112lbs. Yes, that's a big gal but I'm sweet and loving and well...that's just a little bit more of me to love you!! I have a very sweet loving temperament that does well with people but would probably do better in a home with older children as sometimes I don't realize my own size with the wee little ones. I get on great with other pups but haven't had the pleasure yet of meeting any of those strange creatures y'all call a cat. I am a pro at getting out of flimsy fencing so I will need a secure fence or leash walked. I am housetrained already, making it easy for us to get right to the fun stuff...right away. I'd love to share all your adventures from the mundane daily to the weekend exciting. I love getting pets, going for strolls, hiking nature trails and relaxing on the couch watching your favorite TV program. If you're ready for lots of love and affection, I is that big gal for you! All you need to do is fill out my adoption application and I will do the rest!! You can find it at haydudeequine.org
We'll also keep you updated on Apollo's adoption status with email updates.
Photo of Apollo

Apollo

Great Dane

Male, 2 yrs 1 mo
St. Louis, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
WE ARE A TX BASED RESCUE. THIS DOG IS CURRENTLY LOCATED IN TX AND WILL BE TRANSPORTED UPON ADOPTION. Please fill out an adoption application found at haydudeequine.org Apollo - You are the bridge between what was and what will be, my pathway to a new life! Hello all you fantastic people out there, let me introduce myself. My name is Apollo and I'm here hoping to adopt me a family...one that I can say will be all mine! I am about 2 years old and come in at around 130lbs. Yes, that's a big fella but I'm sweet, loving and well...that's just a little bit more of me to love you!! I am an extremely very sweet and affectionate boy that does great with people but I'm kinda like a bull in a china shop so it would be best if I had a home with older kids. I do great with the other pups here but again sometimes I just don't realize my size and would do best with bigger pups. I would hate to accidently hurt them!! I am house and crate trained making it easy for us to get right to the fun stuff...right away. I'd love to share all your adventures from the mundane daily to the weekend exciting. I love getting pets, going for strolls, hiking nature trails, and my nice big soft squishy bed!! If you're ready for lots of love and affection, I is that big boy for you! All you need to do is fill out my adoption application and I will do the rest!! You can find it at haydudeequine.org

Or, how about these Great Danes in cities near Saint Louis, Missouri

These Great Danes are available for adoption close to Saint Louis, Missouri.
We'll also keep you updated on Foster Homes Needed's adoption status with email updates.
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Foster Homes Needed

Great Dane

Male, Young
St. Louis, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
Please consider fostering a Great Dane. It will be the best decision you ever made. Please visit www.foreverfriendsgdri.com Thank you
We'll also keep you updated on Remi's adoption status with email updates.
Photo of Remi

Remi

Great Dane

Male, Young
St. Louis, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
PLEASE READ THE FOLLOWING Forever Friends Great Dane Rescue adopts to qualified homes in Illinois, Indiana, Missouri, and Wisconsin. ADOPTION PROCESS: If you are interested in adopting, please go to http://foreverfriendsgdri.com/the-adoption-process/ and review the Adoption Process information carefully. If our terms and adoption fees are acceptable, please complete the complete the Adoption Application. NOTE: We cannot give any additional information about dogs until your application has been approved. A dog will be listed on Adopt a Pet until it is no longer available for adoption. Forever Friends Great Dane Rescue adopts to qualified homes in Illinois, Indiana, Missouri, and Wisconsin.
We'll also keep you updated on Maple's adoption status with email updates.
Special Needs
Photo of Maple

Maple

Great Dane

Female, Puppy
St. Louis, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, Needs special attention, Needs experienced adopter, Spayed or Neutered, Shots are up-to-date,
Story
PLEASE READ THE FOLLOWING Forever Friends Great Dane Rescue adopts to qualified homes in Illinois, Indiana, Missouri, and Wisconsin. ADOPTION PROCESS: If you are interested in adopting, please go to http://foreverfriendsgdri.com/the-adoption-process/ and review the Adoption Process information carefully. If our terms and adoption fees are acceptable, please complete the complete the Adoption Application. NOTE: We cannot give any additional information about dogs until your application has been approved. A dog will be listed on Adopt a Pet until it is no longer available for adoption. Forever Friends Great Dane Rescue adopts to qualified homes in Illinois, Indiana, Missouri, and Wisconsin.
We'll also keep you updated on Buster's adoption status with email updates.
Photo of Buster

Buster

Great Dane

Male, 3 yrs
Bridgeton, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, Not good with cats, Spayed or Neutered, Shots are up-to-date,
Story
I am Buster, the gentle giant you’ve heard about! At 3 years old, and 113 pounds I’m all about my people. I’m a big softie, and I love hanging out with my humans. I’m good around other dogs, but I don’t need a canine buddy—my humans are all I need! I’m happiest when I’m with my family, so I’d love a home where someone is around most of the time. A big bowl of water (I might dribble a bit, sorry about that!), walks (though I’m still learning to walk politely on a gentle leader), sleeping on a doggie bed by my human's bed at night and being around my humans soaking up all the love and attention are my favorite things. I am not a fan of cats and I will chase them so a home without those pesky creatures is best for me. My ideal home will have a 6-foot fence, I can jump a 4-foot fence (and I will), if in a home with a shorter fence I will have to be taken out on a leash. I’m housebroken and respectful about not getting on the furniture. If you’re looking for a loyal, loving companion who enjoys the simple things in life, I’m your guy. I might be big, but my heart is even bigger!!!! Buster is neutered, up to date on all vaccines, heart worm negative and on heartworm preventative, and microchipped. Buster’s adoption fee is $425.00. Please go to our website aaprescue.org to learn about our adoption process
We'll also keep you updated on Sterling's adoption status with email updates.
Photo of Sterling

Sterling

Great Dane Weimaraner

Male, Adult
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Shots are up-to-date,
Story
If you’re looking for the happiest dog you’re ever going to meet, Sterling is the one for you! Don’t let his pictures fool you—this guy radiates joy and positive energy. He wants to meet everyone because he believes every stranger is one snuggle away from becoming another best friend!Sterling has stunning dark grey Weimaraner coloring with a Great Dane head and floppy lips combined with a lab’s happiness and size. He has such a gentle, loving temperament. He’s about 3 years old and underweight at 54 pounds—he’ll probably be 65-70 pounds once he’s filled out. This resilient stray wandered into his foster’s front yard on a freezing day, shivering until his soulful eyes melted our hearts.Sterling is potty trained, knows basic commands like “sit” and “down,” and gets along beautifully with his foster’s large female dog, small female dog, three cats, adults and kids. He did great meeting the whole pack at the rescue, too!Sterling adapts well when left on his own and has been taught good manners—no begging, no barking or any jumping on furniture. If you sit on the floor, he will plop right next to you, eager for your company. Sterling is ready to settle into his forever home. He’s an easily trainable, happy-go-lucky kinda guy, and he will become the loving 4-legged companion your family has been missing.IMPORTANT: Please read all below, especially if you live outside of Texas, which is where our rescue is located.Apply to adopt on our website: https://www.charmingpetrescue.org/adoptAll of our animals are spayed/neutered, microchipped, and up to date on shots.ALL of our animals are located in Boerne, TX, but transport after adoption is available to other states for a $300 fee for dogs or an additional fee varying by location for cats. If you are seeing our pets posted in your state, that's because you live near a transport stop, they are not currently at that location. Petfinder lists our pets as 'Out of Town' pets at other locations, and Adopt-a-Pet lists our location as a Transport stop. Those are currently the only options they offer to make this clear, so we put this description we've put at the bottom to explain it. You can read more about transport here: www.charmingpetrescue.org/transportWe understand transport is not an option for everyone, but we offer it at the cost we pay the transport company for those who wish to adopt from us.March 12, 2025, 6:56 am
We'll also keep you updated on Brienne's adoption status with email updates.
Photo of Brienne

Brienne

Great Dane

Female, 6 yrs
St. Charles, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Spayed or Neutered,
Story
Meet Brienne, the gentle giant with a heart as big as her stature. At 6 years old and weighing in at a whopping 120 pounds (give or take a few— a lady never discloses her weight!), Brienne is a loving soul who’s experienced the highs and lows of life. Sadly, she was surrendered to animal control when her owners could no longer care for her and the many animals they had. But despite the hardship, Brienne remains as sweet and trusting as ever, ready to find a new home where she can continue sharing her love. Brienne isn’t alone in her journey—she has her best friend by her side, Cadette, a 9-year-old cattle dog who is much smaller in size but just as big in heart. These two have spent their entire lives together, and they find the most comfort in each other’s company. Though they couldn’t be more different in size—Brienne’s towering 120 pounds next to Cadette’s petite frame—they are perfectly matched in spirit and devotion. They share a kennel here, and it’s clear they are each other’s rock. They ask only one simple thing: to be walked together. It’s a small request for two souls who have always been side by side, supporting one another through everything. Brienne and Cadette’s story is one of loyalty, resilience, and love. If you’re looking for a pair of gentle giants who will bring joy and warmth to your life, look no further. Together, they are the perfect combination of strength and tenderness, ready to create new memories and share a lifetime of love with the right family. Will you be the one to offer them the forever home they deserve?

These pups are in Saint Louis, Missouri too!

Below are our newest added Great Danes available for adoption in Saint Louis, Missouri. To see more adoptable Great Danes in Saint Louis, Missouri, use the search tool below to enter specific criteria!
We'll also keep you updated on Lizzy's adoption status with email updates.
Photo of Lizzy

Lizzy

Anatolian Shepherd Alaskan Malamute

Female, 1 yr 11 mos
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Hi there, I'm Lizzy! I'm a young girl with such a bright and happy personality. I love to wiggle my whole body and smile at everyone! I do great on a leash- hardly pull at all. I'm potty-trained and get along well with other dogs. My only request: no kitties please!  If you're interested in adopting me, fill out an adoption application online at www.polkcountyhumanesociety.org/adopt where you will also find a link to request an appointment to meet me. Some pets are in foster homes or may already have an appointment scheduled, so the appointment is important to make sure I will be available to meet you when you come. Polk County Humane Society is located in Bolivar, Missouri, but also makes transports to the Denver, CO, Des Moines, IA and Minneapolis, MN areas at least monthly. For potential adopters in those areas, we can do a virtual visit using FaceTime or another app. Just request an appointment using the same link, but note that you want the visit to be virtual and we will call you at the time of the visit once it is confirmed. For long distance transports, there is an additional $100 fee to cover the cost of the transport ($65) and a health certificate from a veterinarian ($35). Going that last mile home for our sweet pets! All of our pets are neutered or spayed, have vaccinations appropriate for their age, treated with flea/tick/heartworm prevention, dewormed and dogs are also microchipped. ##1971509##
We'll also keep you updated on Moxie's adoption status with email updates.
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Photo of Moxie

Moxie

Anatolian Shepherd

Female, 2 yrs
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Hi, I'm Moxie! I look to be about 2 years old and I am the sweetest girl. I've been wandering the neighborhood on 466th road and the neighbors have been taking care of me. Do I look familiar to anyone?  ##2336263##
We'll also keep you updated on CHAMP's adoption status with email updates.
Photo of CHAMP

CHAMP

Bullmastiff

Male, 2 yrs
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Champ is a very good boy who is already housetrained, crate trained, and knows a few commands. He has been around children, cats and other dogs.

Search for a Great Dane puppy or dog

Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Saint Louis, Missouri.

Great Dane puppies and dogs in nearby cities

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Related breeds in Saint Louis, Missouri

Great Dane shelters & rescues in Saint Louis, Missouri

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Saint Louis, Missouri. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Shelter

1.8 miles

Polk County Humane Society - St. Louis Transport

10900 Sunset Hills Plaza, St. Louis, MO 63127

Pet Types: cats, dogs

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Rescue

6.8 miles

Hay Dude Critter Rescue - MO transport

St. Louis, MO 63111

Pet Types: cats, dogs, horses

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Rescue

11.3 miles

Forever Friends Great Dane Rescue - Missouri

St. Louis, MO 63017

Pet Types: dogs

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Rescue

14.7 miles

All About Paws

Po Box 621, Bridgeton, MO 63044

Pet Types: dogs

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Shelter

16.4 miles

Five Acres Animal Shelter

1099 Pralle Lane, St. Charles, MO 63303

Pet Types: cats, dogs

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Rescue

16.4 miles

Charming Pet Rescue - MO Transport Stop

St. Louis, MO 63303

Pet Types: dogs

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Rescue

29.8 miles

Hope Animal Rescues

PO Box 397, Godfrey, IL 62035

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

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Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

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