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Mastiff puppies and dogs in North Carolina

Looking for a Mastiff puppy or dog in North Carolina? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff in North Carolina Search for a Mastiff puppy or dog Mastiff puppies and dogs in North Carolina cities Mastiff shelters and rescues in North Carolina Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in North Carolina

Below are our newest added Mastiffs available for adoption in North Carolina. To see more adoptable Mastiffs in North Carolina, use the search tool below to enter specific criteria!
We'll also keep you updated on SIMO's adoption status with email updates.
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SIMO

Mastiff

Male, 4 yrs
Clinton, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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We'll also keep you updated on Yeti's adoption status with email updates.
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Yeti

Mastiff/Black Mouth Cur

Male, 5 yrs
New Bern, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
Please visit our website, www.colonialcapitalhs.org to fill out an application today!

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We'll also keep you updated on CECE MASTIFF MIX's adoption status with email updates.
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CECE MASTIFF MIX

Mastiff

Female, Young
Charlotte, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained,
Story
Meet Cece: The Sweet and Shy Boxer-Mastiff Mix! Cece is a stunning one-year-old Boxer-Mastiff mix who weighs 72 lbs and has a heart as big as her frame. Raised with love after her mom tragically passed when Cece was just a tiny puppy, she was bottle-fed and cared for by a kind woman who helped her grow into the sweet, gentle girl she is today.Cece’s shyness is part of her charm—she’s still learning to trust the world and is looking for a patient, loving family to help her gain confidence. While she may take a little time to warm up, once she does, you’ll find her to be incredibly affectionate and loyal. Her calm demeanor and soft, soulful eyes will melt your heart, and she’s happiest in quiet, safe spaces where she can feel secure.Cece is perfect for someone who understands the beauty of earning a shy dog’s trust and is ready to give her the time and love she needs to blossom. In return, Cece will be a devoted companion who will love you unconditionally. Are you the special someone Cece is waiting for?  ccrnewengland@gmail.com  PLEASE NOTE:   Our dogs and cats are fostered in Tennessee and can transport weekly up to the Northeast region.  Request an application and learn more about Critter Cavalry at https://www.crittercavalry.com/adoption.January 6, 2025, 7:38 pm

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We'll also keep you updated on Odin's adoption status with email updates.
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Odin

Mastiff

Male, Adult
Stokesdale, NC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Not good with cats, House-trained,
Story
Odin is a 3 year old English mastiff we have had sense he was a puppy. He loves sleeping and cuddling. And has a great personality and very loyal. He is a little skitage at times but a very well rounded dog. He does have a little bit of a problem eating sometimes. He does not like leases at all. He listens very well, and has no problems running away or not listening. We need to find him a loving home as soon as possible. He needs more space and that's something we can't supply right now, with family challenges we are having

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We'll also keep you updated on DOUG's adoption status with email updates.
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DOUG

Mastiff/Shar Pei

Male, 2 yrs
Raleigh, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
Hi there, I`m Doug, and I`m the sweetest pup you`ll ever meet! I love nothing more than cuddling up with my favorite humans and soaking up all the attention. My cross-eyed look may make me a bit goofy, but that just adds to my charm. I`m ready to shower you with all the love and affection I have to offer. If you`re looking for a loyal, snuggly companion, I`m your guy! Let`s create some unforgettable memories together.I currently weigh ~80 lbs but I need to gain some weight to look and feel my best.How did I get here? Transferred from Wake County Animal Center.**I have a sophisticated medical history- please speak with an adoption specialist for details.**~My adoption fee is $120.00.~

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We'll also keep you updated on SHEBA STAR's adoption status with email updates.
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SHEBA STAR

Mastiff/Labrador Retriever

Female, 4 yrs 2 mos
Chapel Hill, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
Hi there, my name is Sheba! I may be almost 100lbs, but I have very good leash manners and am a gentle giant on walks! Although my history is limited, I seem to prefer a home with older adults that are calm and respectful. I also seem to be dog selective, and would likely thrive in a home where I am the only dog and can soak up all the love! Thank you for considering me, I would love to be your best friend and resident couch potato!Dog Day Out Information: Sheeba Star is a couch potato. She prefers people watching and enjoys a lovely picnic in the sun. No long walks, please.My adoption fee has been fully sponsored.Adopt me and pay $0.00!!!INSIGHTS FROM MY DOG DAY OUT:`Sheba Star was very easy going and friendly for her dog day out adventure. We went to a coffee shop and did a short walk in the woods nearby. She is good on a leash, but doesn’t like to walk very far or fast. Everything she did was at her own, chill pace. After that, we went to the fire station and said hello to the firefighters. Sheba Star loved to meet new people and just hung out with them. She does need a little assistance getting in and out of a car. Overall we had a great time and she will make a great companion for someone looking for an easy going dog.`

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in North Carolina.

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Mastiff puppies and dogs in North Carolina cities

Mastiff Puppies near me Mastiff in Aberdeen Mastiff in Albemarle Mastiff in Angier Mastiff in Apex Mastiff in Archdale Mastiff in Asheboro Mastiff in Asheville Mastiff in Ayden Mastiff in Belmont Mastiff in Bessemer City Mastiff in Black Mountain Mastiff in Boiling Spring Lakes Mastiff in Boone Mastiff in Brevard Mastiff in Burlington Mastiff in Butner Mastiff in Carolina Beach Mastiff in Carrboro Mastiff in Cary Mastiff in Chapel Hill Mastiff in Charlotte Mastiff in Cherryville Mastiff in Clayton Mastiff in Clemmons Mastiff in Clinton Mastiff in Concord Mastiff in Conover Mastiff in Cornelius Mastiff in Davidson Mastiff in Dunn Mastiff in Durham Mastiff in Eden Mastiff in Edenton Mastiff in Elizabeth City Mastiff in Elon Mastiff in Erwin Mastiff in Fairview Mastiff in Farmville Mastiff in Fayetteville Mastiff in Fletcher Mastiff in Forest City Mastiff in Fuquay Varina Mastiff in Garner Mastiff in Gastonia Mastiff in Gibsonville Mastiff in Goldsboro Mastiff in Graham Mastiff in Granite Falls Mastiff in Greensboro Mastiff in Greenville Mastiff in Hamlet Mastiff in Harrisburg Mastiff in Havelock Mastiff in Henderson Mastiff in Hendersonville Mastiff in Hickory Mastiff in High Point Mastiff in Hillsborough Mastiff in Holly Springs Mastiff in Hope Mills Mastiff in Huntersville Mastiff in Indian Trail Mastiff in Jacksonville Mastiff in Kannapolis Mastiff in Kernersville Mastiff in Kill Devil Hills Mastiff in King Mastiff in Kings Mountain Mastiff in Kinston Mastiff in Knightdale Mastiff in Laurinburg Mastiff in Leland Mastiff in Lenoir Mastiff in Lewisville Mastiff in Lexington Mastiff in Lincolnton Mastiff in Lumberton Mastiff in Maggie Valley Mastiff in Marion Mastiff in Matthews Mastiff in Mebane Mastiff in Mills River Mastiff in Mint Hill Mastiff in Mocksville Mastiff in Monroe Mastiff in Mooresville Mastiff in Morehead City Mastiff in Morganton Mastiff in Morrisville Mastiff in Mount Airy Mastiff in Mount Holly Mastiff in Mount Olive Mastiff in Nashville Mastiff in New Bern Mastiff in Newport Mastiff in Newton Mastiff in Oak Island Mastiff in Oak Ridge Mastiff in Oxford Mastiff in Pinehurst Mastiff in Pineville Mastiff in Pleasant Garden Mastiff in Raleigh Mastiff in Reidsville Mastiff in Roanoke Rapids Mastiff in Rockingham Mastiff in Rocky Mount Mastiff in Roxboro Mastiff in Salisbury Mastiff in Sanford Mastiff in Sawmills Mastiff in Selma Mastiff in Shelby Mastiff in Siler City Mastiff in Smithfield Mastiff in Southern Pines Mastiff in Spring Lake Mastiff in Stallings Mastiff in Statesville Mastiff in Summerfield Mastiff in Tarboro Mastiff in Thomasville Mastiff in Trinity Mastiff in Unionville Mastiff in Valdese Mastiff in Wadesboro Mastiff in Wake Forest Mastiff in Walkertown Mastiff in Washington Mastiff in Waynesville Mastiff in Weddington Mastiff in Wendell Mastiff in Whiteville Mastiff in Williamston Mastiff in Wilmington Mastiff in Wilson Mastiff in Winston Salem Mastiff in Winterville Mastiff in Woodfin Mastiff in Zebulon

Mastiff shelters & rescues in North Carolina

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in North Carolina. Browse these Mastiff rescues and shelters below.

Here are a few organizations

Rescue

Colonial Capital Humane Society

PO Box 326, New Bern , NC 28563

Pet Types: cats, dogs, rabbits

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Shelter

Sampson County Animal Shelter

168 Agriculture Place, Clinton , NC 28328

Pet Types: cats, dogs

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Rescue

Humane Society of Eastern Carolina

3520 Tupper Drive, Greenville , NC 27834

Pet Types: cats, dogs

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Rescue

SPCA of Wake County

200 Petfinder Lane, Raleigh , NC 27603

Pet Types: cats, dogs, rabbits, small animals

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog ?

We've got all the info you need on adopting and caring for a Mastiff puppy . Check out the links below for everything you ever wanted to know about Mastiff puppies and adults .

Mastiff information

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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